FDA limiting acetaminophen; CMC researching the issue

FDA limiting acetaminophen; CMC researching the issue

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by KELLIE PATTERSON / NewsChannel 36

WCNC.com

Posted on January 14, 2011 at 5:25 PM

CHARLOTTE, N.C. – On Thursday the Food and Drug Administration announced that they will limit the amount of acetaminophen that can be included in a dose of a prescription drug.

The FDA made the announcement because it continues to receive reports of “severe liver injury” from overdoses of the popular medication. Acetaminophen is widely used and can be found in Tylenol, Exxcedrin, NyQuil, TheraFlu and stronger prescription-only medicines like Vicodin and Percocet. 

It becomes a problem when someone takes more than a prescribed dose of an acetaminophen product in a 24 hour time period, or when someone takes more than one acetaminophen product at the same time.

50 percent of liver failure cases are brought on by intentional or accidental overdose of acetaminophen products.

The announcement is strictly about prescription drugs, but the word of caution extends to over-the-counter drugs as well. The FDA wants to make sure people don’t take more than 4,000 milligrams of acetaminophen in one day.

By the numbers:

Someone who takes two Extra-Strength Tylenols, every six hours, hits that maximum 4,000 mg dose.

If you add in two tablespoons of NyQuil before bed, you would be 650 mg over the maximum.

Over several days, that can add up.

Carolinas Medical Center is a part of a large research effort on the issue.

It’s only by doing carefully controlled and well-designed studies and putting a large number of patients together that we’ll really be able to make progress and move the field forward,” says Dr. Herbert Bonkovsky

To participate in the research, contact Gale Groseclose at 704-355-4875 or e-mail gale.groseclose@carolinashealthcare.org
 

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