CHARLOTTE, N.C.-- Carolina's DeAngelo Williams missed his second straight practice with a sprained ankle, which could leave replacement quarterback Matt Moore without the Panthers' top running threat against Tampa Bay.
With Jake Delhomme sitting out again Thursday with a broken finger on his throwing hand, Moore is expected to get his first start since 2007.
Williams was injured in last Sunday's loss to the New York Jets and hasn't practiced this week.
Receivers Muhsin Muhammad (knee) and Dwayne Jarrett (ankle) also missed practice, leaving Steve Smith as Carolina's only healthy regular receiver.
Running back Jonathan Stewart (Achilles' tendon) and fullback Brad Hoover (ankle) practiced after sitting out Wednesday.